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Malaria-Free Safaris South Africa: Your 2025 Guide to Safe and Spectacular Adventures

Planning a safari is exciting, but the risk of malaria can be a concern when travelling with family or prefer extra peace of mind. Luckily, South Africa offers an array of malaria-free safari destinations that provide all the thrills of a wildlife adventure without worry. In this guide, we’ll explore the best malaria-free safari options in South Africa for 2025, highlighting top reserves, the best times to visit, and why these areas are perfect for a safe, unforgettable safari experience.

Map of Malaria in Africa
Map of Malaria in Africa

Why Choose a Malaria-Free Safari in South Africa?

Choosing a malaria-free safari means you can fully enjoy your adventure without needing anti-malarial medication or worrying about the risks associated with malaria. This is particularly important for families with young children, pregnant women, and travellers who prefer to minimize health risks while still experiencing the wonders of an African safari.

Malaria-free regions in South Africa are primarily located in the southern and eastern parts of the country, away from the higher-risk areas of the northeast. These regions offer rich wildlife experiences, including the chance to see the Big Five, stunning landscapes, luxurious accommodations, and a variety of activities suitable for all ages.

Malaria Mosquito

Top Malaria-Free Safari Destinations in South Africa

Madikwe Game Reserve

Located near the Botswana border, Madikwe Game Reserve is one of the largest malaria-free reserves in South Africa. It’s home to the Big Five and is known for its luxury lodges and excellent game viewing.

Madikwe Game Reserve South Africa
Madikwe Game Reserve South Africa
  • Highlights: Big Five sightings, wild dogs, luxury lodges, and family-friendly accommodations.

  • Best Time to Visit: April to October for the best game viewing.


Pilanesberg National Park

Pilanesberg National Park is just a short drive from Johannesburg and offers a convenient, malaria-free safari experience. The park is set within an ancient volcanic crater, providing unique and varied landscapes.

Pilanesberg National Park
Pilanesberg National Park
  • Highlights: Big Five, over 300 bird species, and proximity to Sun City Resort for additional family activities.

  • Best Time to Visit: May to September during the dry season.

Addo Elephant National Park

Addo Elephant National Park, located in the Eastern Cape, is famous for its large elephant herds and is also home to the Big Seven, including the southern right whale and great white shark.

Addo Elephant National Park
Addo Elephant National Park

  • Highlights: Elephant herds, diverse ecosystems, and the opportunity to combine a safari with coastal experiences.

  • Best Time to Visit: May to September for optimal wildlife viewing.

Shamwari Game Reserve

Shamwari Game Reserve is a leader in conservation and offers an educational experience alongside top-notch game viewing. The reserve is home to the Big Five and provides family-friendly lodges with activities tailored to children.

  • Highlights: Conservation programs, luxury lodges, and educational experiences for children.

  • Best Time to Visit: Year-round, with excellent wildlife sightings during the dry season (May to September).

Waterberg Region

The Waterberg region, particularly the Welgevonden Game Reserve, is a UNESCO Biosphere Reserve known for its stunning landscapes and diverse wildlife. It’s a perfect destination for a more remote and tranquil safari experience.

Qwabi Private Game Reserve: Waterberg
Qwabi Private Game Reserve: Waterberg

  • Highlights: Big Five, beautiful landscapes, and various outdoor activities like hiking and horseback safaris.

  • Best Time to Visit: May to September.

What to Expect on a Malaria-Free Safari

Malaria-free safaris in South Africa offer all the excitement and adventure of traditional safaris but with added peace of mind. Here’s what you can expect:

Lions Walking in front of safari truck

  • Diverse Wildlife: Expect to see the Big Five, along with various other species, including cheetahs, wild dogs, and an abundance of birdlife.

  • Luxury Accommodations: Many malaria-free reserves feature luxurious lodges catering to families, couples, and solo travellers.

  • Family-Friendly Activities: From Junior Ranger programs to educational bush walks, malaria-free reserves are particularly well-suited for families with children.

  • Cultural Experiences: Some reserves offer opportunities to visit local communities and learn about the area's rich cultural heritage.

Best Time to Visit Malaria-Free Safari Areas in South Africa

While South Africa is a year-round safari destination, the best time to visit malaria-free areas typically aligns with the dry season, when wildlife is more concentrated around water sources.

  • Winter (May to September): The dry season is ideal for game viewing, as the vegetation is thinner, and animals congregate around waterholes.

  • Spring (September to November): Spring offers a mix of good wildlife viewing and lush green landscapes, making it a beautiful time to visit.

  • Summer (December to February): While the landscape is green and vibrant, game viewing can be more challenging due to thicker vegetation. However, this is the best time for birdwatching.

  • Autumn (March to April) is a great time for mild weather and fewer tourists, with the bonus of stunning sunsets and beautiful scenery.


Luxury Malaria-Free Safari Experiences

For those seeking a luxury safari experience in a malaria-free zone, South Africa offers several outstanding options:

  • Madikwe Game Reserve: Home to some of the country’s most luxurious lodges, including Madikwe Hills and Molori Safari Lodge, where you can enjoy private plunge pools, gourmet dining, and personalized service.

  • Shamwari Game Reserve: Renowned for its conservation efforts, Shamwari offers luxury lodges like Eagles Crag and Long Lee Manor, with top-tier amenities and exceptional game viewing.

  • Welgevonden Game Reserve (Waterberg Region): This exclusive, malaria-free reserve features luxury lodges, such as Clifftop Exclusive Safari Hideaway, which provides an intimate and serene safari experience.

Shamwari Game Reserve
Shamwari Game Reserve

Tips for Planning Your Malaria-Free Safari

To make the most of your malaria-free safari in South Africa, consider the following tips:

  • Book Early: Malaria-free reserves are famous, especially for family safaris, so it's advisable to book your accommodations well in advance.

  • Choose the Right Reserve: Consider your travel group’s needs—family-friendly amenities, luxury accommodations, or specific wildlife experiences—and select a reserve that matches those preferences.

  • Pack Accordingly: While you won’t need anti-malarial medication, pack essentials like sunscreen, hats, and comfortable, neutral-coloured clothing for game drives.

Elephant and Calf on Safari

Conclusion

A malaria-free safari in South Africa offers the perfect combination of safety, comfort, and adventure. Whether travelling with family and friends or on a solo adventure, these destinations provide an unforgettable safari experience without worrying about malaria. Ready to plan your next safari?


Craig Howes is a professional wildlife photographer who has traveled extensively throughout Africa. The World Travel Awards named him Safari Influencer of the Year 2020.

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